What’s the Link Between Lupus and Arthritis?

By: Researcher Taymur

Understanding Lupus and Arthritis

Lupus (systemic lupus erythematosus) is a common symptom of arthritis. The distinctive feature of rheumatoid arthritis is inflammatory arthritis. Lupus arthritis tends to be less damaging than rheumatoid arthritis. However, rheumatoid arthritis and lupus are genetically related, and one person can experience the characteristics of these two distinct diseases.

It’s called comorbidity when a person has two different illnesses. One report Trusted Source notes that the comorbidity of lupus and rheumatoid arthritis might be genetically based.

It can cause lupus and arthritis only by one gene in your body.

Understanding Arthritis

However the inflammation of the joints is arthritis by definition. So from simple stiffness to swelling and pain, it can cause everything. Therefore according to CDC Trusted Source, 25.6% of arthritis patients suffer severe joint pain and 37.7% say the pain has an impact on their daily lives.

This inflammatory disorder is due to roughness and joint swelling. Your joints may have a limited scale of motion if you have arthritis. The expansion and bending of the joints may be stopped and pain, discomfort and eventual impairment can result.

Understanding the Genetic Link

A genetic link between rheumatoid lupus and arthritis was identified in a 2007 study. This link is linked to STAT4 gene mutations.

The risk of developing lupus is double in those who have a mutated version of that gene. The chance of rheumatoid arthritis is also 60 percent higher.

Therefore scientists do not know what causes the transformation of the STAT4 gene. So you know that the chance of auto-immune disorders increases as it occurs. However in accordance with the United States. Because STAT4 gene mutations also increase the risk of juvenile idiopathy arthritis and systemic scleroderma at the Library National for Genetics Home Reference. Therefore skin tightening and descending and supporting connective tissue are the main characteristics for the latter disease.

Unfortunately, it isn’t easy to know if you have a STAT4 version. Because genetic testing is still at its earliest stage and it may take decades for researchers to establish reliable public studies.

Therefore all research in the STAT4 gene in universities or medical institutions has been carried out to date. Because such studies are the way to learn about the link between genes and autoimmune diseases. So one day, they could lead to new forms of treatment that are more effective.

Understanding Lupus and Rheumatoid Arthritis

However genetic link between lupus and rheumatoid arthritis may lead to similar treatments for both diseases. Similarly to order to control flares and to minimize organ damage, you may need to use a series of therapies based on your symptoms.

Therefore rheumatoid arthritis and lupus arthritis could require medicines to prevent joint damage and to minimize painful swelling. Above all any arthritis treatment plan must include physical treatment, which includes basic strains, joint stiffness exercises and joint protection instructions.


However lupus arthritis is less joint damaging than rheumatoid arthritis according to the Lupus Fund of America. So nevertheless, less than 10% of people with this type of arthritis suffer from joint deformities.

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