The Hidden Connection Between Fat and Fibromyalgia
By: Dr Alex Robber
Carrying surplus body weight improves pain rates in individuals with fibromyalgia and the magnitude of extensive pain; it also improves the seriousness of other symptoms of chronic pain syndrome. Studies have shown that people who are overweight with fibromyalgia are not as physically strong or flexible, have more problems with sleep, experience higher levels of anxiety and depression and experience lower quality of life than healthy people with fibromyalgia.
Therefore according to Akiko, PhD, an investigator at the Pain Management Center at Utah University in Salt Lake City, the connection between obesity and pain is powerful. “Research indicates obesity in nearly all chronic pain situations, including fibromyalgia and osteoarthritis, improves symptom severity and pain sensitivity,” she claims.
The more pain they have, she says, the more individuals weigh. For instance, a 2015 article on the pain-obesity link released in Pain Management revealed that individuals who are overweight (body mass index[ BMI] 25–25,9 kg / m2) had 20% more acute pain than individuals who are healthy, while those who are obese (BMI 30–34 kg / m2) or very obese (BMI 35–39 kg / m2) had 68% and 136% more pain, respectively.
A Lot of Pain
Overloaded joints explain some of the association between pain and fibromyalgia, Akiko suggests. However “The greater your weight, the more it loads and puts stress and strain on your joints, especially in the reduced body areas. This can adversely affect your amount of pain,” she suggests.
Therefore Akiko and her peers assessed pain and other fibromyalgia symptoms in 215 individuals with the syndrome in a 2010 research released in the Journal of Pain, discovering that obese individuals had increased pain sensitivity relative to those with reduced weights, and that this sensitivity was greater in reduced body fields. Similar, lower impacts were noted in individuals with overweight.
“In the reduced extremity, this extra sensitivity also points to mechanical stress as a cause of fibromyalgia pain,” she suggests.
Inflammation Weighing in Body
Cells in fat tissue are chemically active, releasing an amount of proteins and other chemicals that boost inflammation throughout the body, Akiko claims.
“Researchers are beginning to match obesity with a generalized state of low-grade continual inflammation, because” she claims. “Although fibromyalgia is not an inflammatory disease such as rheumatoid arthritis, enhanced general inflammation is likely to play a part in growing pain and sensitivity.”
One factor may be an insulin-like growth factor-1 (IGF-1) growth hormone, which decreases as BMI increases. However According to Jan, PhD investigator at the Department of Rheumatology and Inflammation Research at the University of Goteborg, Sweden, IGF-1 appears to decrease fibromyalgia-related fatigue, which nurses often rank as the second most disturbing symptom–after pain–of the syndrome.
So, Jon and peers evaluated blood concentrations of IGF-1 and other interventions in a 2013 research of Arthritis Research & Therapy in 48 individuals with fibromyalgia participating in a controlled exercise program. They discovered that 15 weeks of twice-weekly 45-minute walking sessions considerably increased concentrations of IGF-1 and reduced tiredness in respondents with normal weight, overweight and obesity, although the impacts were faster in lighter-weight people.
“It is not known how exercise reduces fatigue, but our information show that IGF-1 activity is engaged,” said Jon. “In our latest research, the impact of practice was greatest in lean respondents, but overweight and obese respondents also benefited after six months.”
Weight loss also enhances symptoms of fibromyalgia. Therefore in 2012 study released in Clinical Rheumatology compared people with fibromyalgia who reduced their BMIs by about three points, enough to move most from an obese to overweight classification, with their counterparts remaining the same weight. Because weight losers enhanced considerably in inflammatory protein measurements and nearly all fibromyalgia symptoms, including pain, depression and sleep.
Obesity Vs Pain and Sleep
Akiko other scientists discovered that fibromyalgia obesity decreases the quality of sleep compared to individuals with the syndrome who are healthy-weight. “This poorer sleep can contribute to suffering as well,” she suggests. The physiological pathway in fibromyalgia that connects pain and bad sleep seems to run both ways.
However a research released in The Clinical Journal of Sleep Medicine in 2014 discovered that pain substantially decreased sleep quality among 55 females with fibromyalgia, and bad sleep quality substantially enhanced pain. “Poor sleep also decreases the capacity of people to deal with pain, making it more difficult for them to concentrate on other stuff and participate in physical activity,” Akiko claims. “It is encouraging that both exercise and weight loss can lead to symptom severity decrease.” Stay Healtizes!
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